Colorado's Route 350 is a U.S. highway that parallels the mountain leg of the historic Santa Fe Trail. Located entirely within the borders of Colorado, this highway meanders from Trinidad, CO eastward to La Junta, near US-50.
Trinidad is worth a stop for the well-preserved Victorian architecture and the WPA cabins at Monument Lake Resort.
This highway is open road of Americana. If you're looking for twisties or adrenaline, this isn't the place. But this ride does offer the motorcyclist high-plains solitude in spades.